Medication guidance of low high density lipoprotein cholesterol

Low high density lipoprotein cholesterol (HDL-C) is common in people who are obese, smoke, and lack physical activity. Therefore, for those with low HDL-C levels, non-drug treatment such as exercise, quitting smoking, and losing weight should be preferred.

Exercise can effectively increase serum HDL-C levels. Additionally, treating the primary diseases that cause decreased HDL-C levels, such as nephrotic syndrome and diabetes, is necessary.

Medication guidance of low high density lipoprotein cholesterol
Medication guidance of low high density lipoprotein cholesterol

When patients with coronary heart disease have increased low-density lipoprotein-cholesterol (LDL-C) levels accompanied by Low high density lipoprotein cholesterol, lipid-lowering treatment should be adopted. Drugs that can increase HDL-C levels, such as nicotinic acid, 0.1-2 grams each time, three times a day, should be selected. Nicotinic acid has significant adverse reactions, and if patients cannot tolerate these reactions, statin drugs can be used as an alternative. These drugs have a mild HDL-C- elevating effect.

Nicotinic acid should also be the first choice when hypertriglyceridemia with low HDL-C needs treatment. When isolated hypohdl-c is accompanied by hypertension, drugs that can reduce HDL-C should not be selected, such as β- Receptor blockers instead of drugs that do not affect HDL-C levels, such as angiotensin-converting enzyme inhibitors and long-acting calcium antagonists. When there is isolated hypohdl-c without other serum lipid abnormalities, drugs that elevate HDL-C are not recommended as the primary prevention of coronary heart disease.

Leave a Comment

Your email address will not be published. Required fields are marked *

Scroll to Top